Publications

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2025

Helmeczi, E, Kroezen, Z, Shanmuganathan, M, Stanciu, AR, Martinez, V, Kurysko, N, Normando, P, Rugani Ribeiro de Castro, I, Machado Schincaglia, R, Kac, G, and Britz-McKibbin, P, 2025. "A Software Tool for Rapid and Automated Preprocessing of Large-Scale Serum Metabolomic Data by Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry". Analytical Chemistry, 97(1), 175-184 View Abstract

Stanciu, AR, Gillespie, C, and Britz-McKibbin, P, 2025. "Environmental Exposures and Health Risks: A Metabolomics Perspective on Exposomics Research". Annual Review of Analytical Chemistry (Palo Alto, Calif.), 071524-125307 View Abstract

Kamal, M, Shanmuganathan, M, Kroezen, Z, Joanisse, S, Britz-McKibbin, P, and Parise, G, 2025. "Senescent myoblasts exhibit an altered exometabolome that is linked to senescence-associated secretory phenotype signaling". American Journal of Physiology-Cell Physiology, 328(2), C440-C451 View Abstract

Padhila, M, Keller, VN, Normando, P, Schincaglia, RM, Freitas-Costa, NC, Freire, SSR, Delpino, FM, de Castro, IRR, Lacerda, EMA, Farias, DR, Kroezen, Z, Shanmuganathan, M, Britz-McKibbin, P, and Kac, G, 2025. "Serum metabolome indicators of early childhood development in the Brazilian National Survey on Child Nutrition (ENANI-2019)". Elife, 97982 View Abstract

Helmeczi, E, Pandya, H, O'Hearn, K, McNally, D, and Britz-McKibbin, P, 2025. "Treatment response variations to a single large bolus of enteral cholecalciferol in vitamin D deficient critically Ill children: Metabolomic insights for precision nutrition". The Journal of steroid biochemistry and molecular biology, 250 (2025) 106720 View Abstract

2024

Barker-Tejeda, TC, Zubeldia-Varela, E, Macías-Camero, A, Alonso, L, Martín-Antoniano, IA, Rey-Stolle, MF, Mera-Berriatua, L, Bazire, R, Cabrera-Freitag, P, Shanmuganathan, M, Britz-McKibbin, P, Ubeda, C, Francino, MP, Barber, D, Ibáñez-Sandín, MD, Barbas, C, Pérez-Gordo, M, and Villaseñor, A, 2024. "Comparative characterization of the infant gut microbiome and their maternal lineage by a multi-omics approach". Nature Communications, 15, 3004 View Abstract

Froude, AM, Pangborn N, Britz-McKibbin, P, MacKillop, J, and Balodis, I, 2024. "Potential Risks from Cannabis-Infused Beverages: A Critical Review". Cannabis, 7(3), 134-166 View Abstract

O'Hearn, K, Menon, K, Albrecht, L, Amrein, K, Britz-McKibbin, P, Cayouette, F, Choong, K, Foster, JR, Fergusson, DA, Floh, A, Fontela, P, Geier, P, Gilfoyle, E, Garcia Guerra, G, Gunz, A, Helmeczi, E, Khamessan, A, Joffe, AR, Lee, L, McIntyre, L, Murthy, S, Parsons, SJ, Ramsay, T, Ryerson, L, Tucci, M, McNally, D, and Critical Care Trials Group, C, 2024. "Rapid normalization of vitamin D deficiency in PICU (VITdALIZE-KIDS): study protocol for a phase III, multicenter randomized controlled trial". Trials, 25(1), 619 View Abstract

Baskaran, K, Moshkovich, M, Hart, L, Shah, N, Chowdhury, F, Shanmuganathan, M, Britz-McKibbin, P, and Pai, N, 2024. "The role of urine metabolomics in the diagnosis and management of adult and pediatric Crohn's disease and ulcerative colitis". Biomarkers, 30(1), 104-113 View Abstract

2023

Lanktree, M, Perrot, N, Smyth, A, Chong, M, Narula, S, Shanmuganathan, M, Kroezen, Z, Britz-McKibbin, P, Berger, M, Krepinsky, J, Pigeyre, M, Yusuf, S, and Paré, G, 2023. "A novel multi-ancestry proteome-wide Mendelian randomization study implicates extracellular proteins, tubular cells, and fibroblasts in estimated glomerular filtration rate regulation". Kidney International, 104(6), 1170-1184 View Abstract

Shanmuganathan, M, Bogert, M, Kroezen, Z, Britz-McKibbin, P, and Atkinson, S, 2023. "Dynamic Metabolic Signatures of Choline and Carnitine across Healthy Pregnancy and in Cord Blood: Association with Maternal Dietary Protein". The Journal of Nutrition, 153, 999-1007 View Abstract

Azab, S, Shanmuganathan, M, de Souza, R, Kroezen, Z, Desai, D, Williams, N, Morrison, K, Atkinson, S, Teo, K, Azad, M, Simons, E, Moraes, T, Mandhane, P, Turvey, S, Subbarao, P, Britz-McKibbin, P, and Anand, S, 2023. "Early sex-dependent differences in metabolic profiles of overweight and adiposity in young children: a cross-sectional analysis". BMC Medicine, 21(176) View Abstract

Bruce, C, Shanmuganathan, M, Azab, S, Britz-McKibbin, P, Anand, S, Souza, Rd, and Stearns, J, 2023. "Effects of diet on the microbiome and serum metabolome of South Asian infants at 1 year". The Journal of Nutrition, 153, 470-482 View Abstract

Velichka, J, Kidd, K, Munkittrick, K, Shanmuganathan, M, Britz-McKibbin, P, and Curry, A, 2023. "Elements and omega-3 fatty acids in fishes along a large, dammed river". Environmental Pollution, 336, 122375 View Abstract

Ly, R, Torres, L, Ly, N, and Britz-McKibbin, P, 2023. "Expanding Lipidomic Coverage in Multisegment Injection-Nonaqueous Capillary Electrophoresis-Mass Spectrometry via a Convenient and Quantitative Methylation Strategy". Analytical Chemistry, 95, 17513-17524 View Abstract

Mente, A, Britz-McKibbin, P, and Yusuf, S, 2023. "Improving precision in estimating diet–disease relationships with metabolomics". European Society of Cardiology, 44, 570-572 View Abstract

Rafiq, T, Stearns, J, Shanmuganathan, M, Azab, S, Anand, S, Thabane, L, Beyene, J, Williams, N, Morrison, K, Teo, K, Britz-McKibbin, P, and de Souza, R, 2023. "Integrative multiomics analysis of infant gut microbiome and serum metabolome reveals key molecular biomarkers of early onset childhood obesity". Heliyon, 9(e16651) View Abstract

Ly, R, MacIntyre, B, Philips, S, McGlory, C, and Mutch, D, 2023. "Lipidomic studies reveal two specific circulating phosphatidylcholines as surrogate biomarkers of the omega-3 index". Journal of Lipid Research, 64(11), 100445 View Abstract

Mathiaparanama, S, Nori de Macedo, A, Gill, B, Keenan, K, Gonska, T, Pedder, L, Hill, S, and Britz-McKibbin, P, 2023. "Rapid chloride and bicarbonate determination by capillary electrophoresis for confirmatory testing of cystic fibrosis infants with volume-limited sweat specimens". Journal of Cystic Fibrosis, 22, 66-72 View Abstract

MacIntyre, B, Shanmuganathan, M, Klingel, S, Kroezen, Z, Helmeczi, E, Seoh, N, Martinez, V, Chabowski, A, Feng, Z, Britz-McKibbin, P, and Mutch, D, 2023. "Urinary Metabolite Profiling to Non-Invasively Monitor the Omega-3 Index: An Exploratory Secondary Analysis of a Randomized Clinical Trial in Young Adults". Metabolites, 13(10), 1071 View Abstract

Mathiaparanam, S, Gill, B, Sathish, T, Paré, G, Teo, K, Yusuf, S, and Britz-McKibbin, P, 2023. "Validation of Urinary Thiocyanate as a Robust Biomarker of Active Tobacco Smoking in the Prospective Urban and Rural Epidemiological Study". Nicotine and Tobacco Research, 25, 1291-1301 View Abstract

2022

Helmeczi, E, Fries, E, Perry, L, Choong, K, O-Hearn, K, McNally, D, and Britz-McKibbin, P, 2022. "A high-throughput platform for the rapid screening of vitamin D status by direct infusion-MS/MS". Journal of Lipid Research, 63(5) View Abstract

Azab, SM, de Souza, RJ, Ly, R, Teo, KK, Atkinson, SA, Morrison, KM, Anand, SS, and Britz-McKibbin, P, 2022. "Non-esterified fatty acids as biomarkers of diet and glucose homeostasis in pregnancy: The impact of fatty acid reporting methods: NEFA reporting methods affect dietary and cardiometabolic endpoints". Prostaglandins, Leukotrienes and Essential Fatty Acids, 176(102378) View Abstract

Ly, R, Ly, N, Sasaki, K, Suzuki, M, Kami, K, Ohashi, Y, and Britz-McKibbin, P, 2022. "Nontargeted serum lipid profiling of nonalcoholic steatohepatitis by multisegment injection-nonaqueous capillary electrophoresis-mass spectrometry: A multiplexed separation platform for ionic lipids". Journal of Proteome Research, 20, 768-777 View Abstract

Mangalakumari, J, Vaseghi-Shanjani, M, Afkhami, S, Grondin, J, Kang, A, D’Agostino, M, Yao, Y, Jain, S, Zganiacz, A, Kroezen, Z, Shanmuganathan, M, Singh, R, Dvorkin-Gheva, A, Britz-McKibbin, P, Khan, W, and Xing, Z, 2022. "Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis". Nature Immunology, 23, 1687-1702 View Abstract

Sikorski, C, Azab, S, de Souza, R, Shanmuganathan, M, Desai, D, Teo, K, Atkinson, S, Morrison, K, Gupta, M, Britz-McKibbin, P, and Anand, S, 2022. "Serum metabolomic signatures of gestational diabetes in South Asian and white European women". BMJ Journals, 10(e002733) View Abstract

Rafiq, T, Azab, S, Anand, S, Thabane, L, Shanmuganathan, M, Morrison, K, Atkinson, S, Stearns, J, Teo, K, Britz-McKibbin, P, and de Souza, R, 2022. "Sources of Variation in Food-Related Metabolites during Pregnancy". Nutrients, 14(2503) View Abstract

Mathiaparanam, S, Nori de Macedo, A, Mente, A, Poirier, P, Lear, S, Wielgosz, A, Teo, K, Yusuf, S, and Britz-McKibbin, P, 2022. "The Prevalence and Risk Factors Associated with Iodine Deficiency in Canadian Adults". Nutrients, 14(2570) View Abstract

Thirunavukkarasu, S, Teo, K, Britz-McKibbin, P, Gill, B, Islam, S, Paré, G, Rangarajan, S, Duong, M, Lanas, F, Lopez-Jaramillo, P, Mony, P, Pinnaka, L, Kutty, V, Orlandini, A, Avezum, A, Wielgosz, A, Poirier, P, Alhabib, K, Temizhan, A, Chifamba, J, Yeates, K, Kruger, I, Khatib, R, Yusuf, R, Rosengren, A, Zatonska, K, Iqbal, R, Lui, W, Lang, X, Li, S, Hu, B, Dans, A, Yusufali, A, Bahonar, A, O’Donnell, M, McKee, M, and Yusuf, S, 2022. "Variations in risks from smoking between high-income, middle-income, and low-income countries: an analysis of data from 179000 participants from 63 countries". The Lancet Global Health, 10, e216-e226 View Abstract

2021

Shanmuganathan, M, Omair Sarfaraz, M, Kroezen, Z, Philbrick, H, Poon, R, Don-Wauchope, A, Puglia, M, Wishart, D, and Britz-McKibbin, P, 2021. "A Cross-Platform Metabolomics Comparison Identifies Serum Metabolite Signatures of Liver Fibrosis Progression in Chronic Hepatitis C Patients". Frontiers in Molecular Biosciences, 8, 676349 View Abstract

Azab, SM, de Souza, RJ, Lamri, A, Shanmuganathan, M, Kroezen, Z, Schulze, KM, Desai, D, Williams, NC, Morrison, KM, Atkinson, SA, Teo, KK, Britz-McKibbin, P, and Anand, SS, 2021. "Metabolite profiles and the risk of metabolic syndrome in early childhood: a case-control study". BMC Medicine, 19(292) View Abstract

Saoi, M and Britz-McKibbin, P, 2021. "New Advances in Tissue Metabolomics: A Review". Metabolites, 11(10), 672 View Abstract

Rafiq, T, Azab, S, Teo, K, Thabane, L, Anand, S, Morrison, K, de Souza, R, and Britz-McKibbin, P, 2021. "Nutritional metabolomics and the classification of robust dietary biomarkers: A critical review". Advances in Nutrition, 12, 2333–2357 View Abstract

Sikorski, C, Azab, SM, Souza, RD, Shanmuganathan, M, Britz-McKibbin, P, and Anand, S, 2021. "Serum metabolic signatures of Gestational Diabetes in South Asian and white European women". BMJ Open Diabetes Research & Care, Under review View Abstract

Shanmuganathan, M, Kroezen, Z, Gill, B, Azab, S, de Souza, R, Teo, K, Atkinson, S, Subbarao, P, Desai, D, Anand, S, and Britz-McKibbin, P, 2021. "The maternal serum metabolome by multisegment injection-capillary electrophoresis-mass spectrometry: a high-throughput platform and standardized data workflow for large-scale epidemiological studies". Nature Protocols, 16, 1966-1994 View Abstract

Yamamoto, M, Shanmuganathan, M, Hart, L, Pai, N, and Britz-McKibbin, P, 2021. "Urinary metabolic signatures enable differential diagnosis and therapeutic monitoring of pediatric inflammatory bowel disease". Metabolites, 11(4), 245 View Abstract

2020

Gill, B and Britz-McKibbin, P, 2020. "Biomonitoring of smoke exposures in firefighters: A review". Current Opinion in Environemental Science and Health, 15, 57-65 View Abstract

Hart, L, Farbod, Y, Szamosi, J, Yamamoto, M, Britz-McKibbin, P, Halgren, C, Zachos, M, and Pai, N, 2020. "Effect of Exclusive Enteral Nutrition and Corticosteroid Induction Therapy on the Gut Microbiota of Pediatric Patients with Inflammatory Bowel Disease". Nutrients, 12(6), 1691 View Abstract

Lemay, J, Yamamoto, M, Kroezen, Z, Shanmuganathan, M, Ly, R, Hart, L, Pai, N, and Britz-McKibbin, P, 2020. "Lyophilized fecal short-chain fatty acid and electrolyte determination by capillary electrophoresis with indirect UV detection for assessment of pediatric inflammatory bowel disease". Journal of Pharmaceutical and Biomedical Analysis, 192, 113658 View Abstract

Khan, H, Gallant, R, Zamzam, A, Jain, S, Afxentiou, S, Syed, M, Kroezen, Z, Shanmuganathan, M, Britz-McKibbin, P, Al-Omran, M, Ni, H, Rand, M, and Qadura, M, 2020. "Personalization of aspirin therapy in atherosclerotic patients using light transmission aggregometry". Under review View Abstract

Saoi, M, Kennedy, K, Gohir, W, Sloboda, D, and Britz-McKibbin, P, 2020. "Placental Metabolomics for Assessment of Sex-specific Differences in Fetal Development During Normal Gestation". Scientific Reports, 10, 9399 View Abstract

Gill, B, Jobst, K, and Britz-McKibbin, P, 2020. "Rapid Screening of Urinary 1-Hydroxypyrene Glucuronide by Multisegment Injection–Capillary Electrophoresis–Tandem Mass Spectrometry: A High-Throughput Method for Biomonitoring of Recent Smoke Exposures". Analytical Chemistry, 92(19), 13558–13564 View Abstract

Azab, S, Hum, R, and Britz-McKibbin, P, 2020. "Rapid biomonitoring of perfluoroalkyl substance exposures in serum by multisegment injection-nonaqueous capillary electrophoresis-tandem mass spectrometry". Analytical Science Advances, (in press) View Abstract

Shaw, L, Shaw, D, Hardisty, M, Britz-McKibbin, P, and Verma, D, 2020. "Relationships between inhalable and total hexavalent chromium exposures in steel passivation, welding and electroplating operations of Ontario". International Journal of Hygiene and Environmental Health, 230, 113601 View Abstract

Azab, S, de Souza, R, Teo, K, (FI, Anand, S, Williams, N, Holzschuher, J, McGlory, C, Philips, S, and Britz-McKibbin, P, 2020. "Serum Nonesterified Fatty Acids Have Utility as Dietary Biomarkers of Fat Intake From Fish, Fish Oil, and Dairy in Women". Journal of Lipid Research, 61(6), 933-944 View Abstract

Azab, S, Zamzam, A, Syed, M, Abdin, R, Qadura, M, and Britz-McKibbin, P, 2020. "Serum metabolic signatures of chronic limb-threatening ischemia in patients with peripheral artery disease". Journal of Clinical Medicine, 9, 1877 View Abstract

2019

Saoi, M, Percival, M, Nemr, C, Li, A, Gibala, M, and Britz-McKibbin, P, 2019. "Characterization of the Human Skeletal Muscle Metabolome for Elucidating the Mechanisms of Bicarbonate Ingestion on Strenuous Interval Exercise". Analytical Chemistry, 91(7), 4709-4718 View Abstract

Shanmuganathan, M, Kroezen, Z, Macklai, S, and Britz-McKibbin, P, 2019. "Comprehensive Surveillance of Drugs of Abuse". GIT Laboratory Journal View Abstract

Wellington, N, Macklai, S, and Britz-McKibbin, P, 2019. "Elucidating the Anomalous Binding Enhancement of Isoquinoline Boronic Acid for Sialic Acid Under Acidic Conditions: Expanding Biorecognition Beyond Vicinal Diols". Chemistry - A European Journal, 25(67) View Abstract

Saoi, M, Sasaki, K, Sagawa, H, Abe, K, Kogiso, T, Tokushige, K, Hashimoto, E, Ohashi, Y, and Britz-McKibbin, P, 2019. "High Throughput Screening of Serum γ-Glutamyl Dipeptides for Risk Assessment of Nonalcoholic Steatohepatitis with Impaired Glutathione Salvage Pathway". Journal of Proteome Research View Abstract

Shanmuganathan, M, Macklai, S, Barrenas, C, Kroezen, Z, Kim, M, Zizek, W, Lee, H, and Britz-McKibbin, P, 2019. "High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-capillary Electrophoresis Mass Spectrometry". Journal of Visualized Experiments, 146(e58986) View Abstract

Gohir, W, Kennedy, K, Wallace, J, Saoi, M, Bellissimo, C, Britz-McKibbin, P, Petrik, J, Surette, M, and Sloboda, D, 2019. "High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers". J. Physiol. , 597(12), 3029-3051 View Abstract

Saoi, M, Li, A, McGlory, C, Stokes, T, Von Allmen, MT, Phillips, SM, and Britz-McKibbin, P, 2019. "Metabolic Perturbations From Step Reduction in Older Persons at Risk for Sarcopenia: Plasma Biomarkers of Abrupt Changes in Physical Activity". Metabolites, 9(7), 134 View Abstract

Wellington, N, Shanmuganathan, M, de Souza, R, Zulyniak, M, Azab, S, Bloomfield, J, Mell, A, Ly, R, Desai, D, Anand, S, and Britz-McKibbin, P, 2019. "Metabolic Trajectories Following Contrasting Prudent and Western Diets from Food Provisions: Robust Biomarkers of Short-Term Changes in Habitual Diet". Nutrients, 11(10), 2407 View Abstract

Wild, J, Shanmuganathan, M, Hayashi, M, Potter, M, and Britz-McKibbin, P, 2019. "Metabolomics for improved treatment monitoring of phenylketonuria: urinary biomarkers for non-invasive assessment of dietary adherence and nutritional deficiencies". Analyst View Abstract

Yamamoto, M, Ines Pinto-Sanchez, M, Bercik, P, and Britz-McKibbin, P, 2019. "Metabolomics reveals elevated urinary excretion of collagen degradation and epithelial cell turnover products in irritable bowel syndrome patients". Metabolomics, 15(82) View Abstract

Shanmuganathan, M and Britz-McKibbin, P, 2019. "New Advances in Amino Acid Profiling in Biological Samples by Capillary Electrophoresis-Mass Spectrometry". View Abstract

Shanmuganathan, M and Britz-McKibbin, P, 2019. "New Advances in Screening of Inborn Errors of Metabolism by Capillary Electrophoresis-Mass Spectrometry". View Abstract

Azab, S, Ly, R, and Britz-McKibbin, P, 2019. "Robust Method for High-Throughput Screening of Fatty Acids by Multisegment Injection-Nonaqueous Capillary Electrophoresis–Mass Spectrometry with Stringent Quality Control". Analytical Chemistry, 91(3), 2329-2336 View Abstract

Cherry, N, Aklilu, Y, Beach, J, Britz-McKibbin, P, Elbourne, R, Galarneau, J, Gill, B, Kinniburgh, D, and Zhang, X, 2019. "Urinary 1-hydroxypyrene and Skin Contamination in Firefighters Deployed to the Fort McMurray Fire". Annals of Work Exposures and Health, 63(4), 448-458 View Abstract

Gill, B, Mell, A, Shanmuganathan, M, Jobst, K, Zhang, X, Kinniburgh, D, Cherry, N, and Britz-McKibbin, P, 2019. "Urinary hydroxypyrene determination for biomonitoring of firefighters deployed at the Fort McMurray wildfire: an inter-laboratory method comparison". Analytical and Bioanalytical Chemistry, 411(7), 1397-1407 View Abstract

2018

DiBattista, A, McIntosh, N, Lamoureux, M, Al-Dirbashi, O, Chakraborty, P, and Britz-McKibbin, P, 2018. "Metabolic Signatures of Cystic Fibrosis Identified in Dried Blood Spots For Newborn Screening Without Carrier Identification". Journal of Proteome Research, 18(3), 841-854 View Abstract

Britz-McKibbin, P, 2018. "Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry for Metabolomics: A Robust Platform for High Throughput Metabolite Profiling with Quality Assurance". View Abstract

Nori de Macedo, A, Mathiaparanam, S, Ly, R, and Britz-McKibbin, P, 2018. "Surveying Iodine Nutrition using Kinetic Spectrophotometry: An Integrative Laboratory Experiment in Analytical Chemistry and Population Health". Journal of Chemical Education, 95, 1029-1034 View Abstract

2017

DiBattista, A, Rampersaud, D, Lee, H, Kim, M, and Britz-McKibbin, P, 2017. "High Throughput Screening Method for Systematic Surveillance of Drugs of Abuse by Multisegment Injection–Capillary Electrophoresis–Mass Spectrometry". Anal. Chem., 89(21), 11853–11861 View Abstract

DiBattista, A, McIntosh, N, Lamoureux, M, Al-Dirbashi, OY, Chakraborty, P, and Britz-McKibbin, P, 2017. "Temporal Signal Pattern Recognition in Mass Spectrometry: A Method for Rapid Identification and Accurate Quantification of Biomarkers for Inborn Errors of Metabolism with Quality Assurance.". Anal Chem, 89(15), 8112-8121 View Abstract

Nori de Macedo, A, Mathiaparanam, S, Brick, L, Keenan, K, Gonska, T, Pedder, L, Hill, S, and Britz-McKibbin, P, 2017. "The Sweat Metabolome of Screen-Positive Cystic Fibrosis Infants: Revealing Mechanisms beyond Impaired Chloride Transport". ACS Central Science View Abstract

De Palma, G, Lynch, MDJ, Lu, J, Dang, VT, Deng, Y, Jury, J, Umeh, G, Miranda, PM, Pigrau Pastor, M, Sidani, S, Pinto-Sanchez, MI, Philip, V, McLean, PG, Hagelsieb, M, Surette, MG, Bergonzelli, GE, Verdu, EF, Britz-McKibbin, P, Neufeld, JD, Collins, SM, and Bercik, P, 2017. "Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice.". Sci Transl Med, 9(379) View Abstract

Nori de Macedo, A, Macri, J, Hudecki, PL, Saoi, M, McQueen, MJ, and Britz-McKibbin, P, 2017. "Validation of a Capillary Electrophoresis Assay for Monitoring Iodine Nutrition in Populations for Prevention of Iodine Deficiency: An Interlaboratory Method Comparison". Journal of Applied Laboratory Medicine, 2(1), 649-660 View Abstract

2016

Jafari, N, Ahmed, R, Gloyd, M, Bloomfield, J, Britz-McKibbin, P, and Melacini, G, 2016. "Allosteric Sensing of Fatty Acid Binding by NMR: Application to Human Serum Albumin.". J Med Chem, 59(16), 7457-65 View Abstract

Fernando, S, Shaw, L, Shaw, D, Gallea, M, VandenEnden, L, House, R, Verma, DK, Britz-McKibbin, P, and McCarry, BE, 2016. "Evaluation of Firefighter Exposure to Wood Smoke during Training Exercises at Burn Houses.". Environ Sci Technol, 50(3), 1536-43 View Abstract

Yamamoto, M, Ly, R, Gill, B, Zhu, Y, Moran-Mirabal, J, and Britz-McKibbin, P, 2016. "Robust and High-Throughput Method for Anionic Metabolite Profiling: Preventing Polyimide Aminolysis and Capillary Breakages under Alkaline Conditions in Capillary Electrophoresis-Mass Spectrometry.". Anal Chem, 88(21), 10710-10719 View Abstract

2015

Wenz, C, Barbas, C, Lopez-Gonzalvez, A, Garcia, A, Benavente, F, Sanz-Nebot, V, Blanc, T, Freckleton, G, Britz-McKibbin, P, Shanmuganathan, M, de l'Escaille, F, Far, J, Haselberg, R, Huang, S, Huhn, C, Pattky, M, Michels, D, Mou, S, Yang, F, Neusuess, C, Tromsdorf, N, Baidoo, EEK, Keasling, JD, and Park, SS, 2015. "Interlaboratory study to evaluate the robustness of capillary electrophoresis-mass spectrometry for peptide mapping.". J Sep Sci View Abstract

Sumner, LW, Styczynski, M, McLean, J, Fiehn, O, Jander, G, Liao, J, Sumner, S, Britz-McKibbin, P, Welti, R, Jones, AD, Dorrestein, PC, Bearden, D, and Kaddurah-Daouk, R, 2015. "Introducing the USA Plant, Algae and Microbial Metabolomics Research Coordination Network (PAMM-NET).". Metabolomics, 11(1), 3-5 View Abstract

Badoud, F, Lam, KP, Perreault, M, Zulyniak, MA, Britz-McKibbin, P, and Mutch, DM, 2015. "Metabolomics Reveals Metabolically Healthy and Unhealthy Obese Individuals Differ in their Response to a Caloric Challenge.". PLoS One, 10(8), e0134613 View Abstract

Kuehnbaum, NL, Gillen, JB, Kormendi, A, Lam, KP, DiBattista, A, Gibala, MJ, and Britz-McKibbin, P, 2015. "Multiplexed separations for biomarker discovery in metabolomics: Elucidating adaptive responses to exercise training.". Electrophoresis View Abstract

2014

de Macedo, AN, Teo, K, Mente, A, McQueen, MJ, Zeidler, J, Poirier, P, Lear, SA, Wielgosz, A, and Britz-McKibbin, P, 2014. "A robust method for iodine status determination in epidemiological studies by capillary electrophoresis.". Anal Chem, 86(20), 10010-5 View Abstract

Kuehnbaum, NL, Gillen, JB, Gibala, MJ, and Britz-McKibbin, P, 2014. "Personalized metabolomics for predicting glucose tolerance changes in sedentary women after high-intensity interval training.". Sci Rep, 4, 6166 View Abstract

Badoud, F, Lam, KP, DiBattista, A, Perreault, M, Zulyniak, MA, Cattrysse, B, Stephenson, S, Britz-McKibbin, P, and Mutch, DM, 2014. "Serum and adipose tissue amino acid homeostasis in the metabolically healthy obese.". J Proteome Res, 13(7), 3455-66 View Abstract

2013

Britz-McKibbin, P, 2013. "Expanded newborn screening of inborn errors of metabolism by capillary electrophoresis-electrospray ionization-mass spectrometry (CE-ESI-MS).". Methods Mol Biol, 919, 43-56 View Abstract

Shanmuganathan, M and Britz-McKibbin, P, 2013. "High quality drug screening by capillary electrophoresis: a review.". Anal Chim Acta, 773, 24-36 View Abstract

Kuehnbaum, NL, Kormendi, A, and Britz-McKibbin, P, 2013. "Multisegment injection-capillary electrophoresis-mass spectrometry: a high-throughput platform for metabolomics with high data fidelity.". Anal Chem, 85(22), 10664-9 View Abstract

Kuehnbaum, NL and Britz-McKibbin, P, 2013. "New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era.". Chem Rev, 113(4), 2437-68 View Abstract

de Macedo, AN, Jiwa, MIY, Macri, J, Belostotsky, V, Hill, S, and Britz-McKibbin, P, 2013. "Strong anion determination in biological fluids by capillary electrophoresis for clinical diagnostics.". Anal Chem, 85(22), 11112-20 View Abstract

2012

White, CE, Gavina, JMA, Morton, R, Britz-McKibbin, P, and Finan, TM, 2012. "Control of hydroxyproline catabolism in Sinorhizobium meliloti.". Mol Microbiol, 85(6), 1133-47 View Abstract

Harskamp, J, Britz-McKibbin, P, and Wilson, J, 2012. "Functional Screening of Cytochrome P450 Activity and Uncoupling by Capillary Electrophoresis". Anal. Chem., 84(2), 862-866 View Abstract

Shanmuganathan, M and Britz-McKibbin, P, 2012. "Functional screening of pharmacological chaperones via restoration of enzyme activity upon denaturation.". Biochemistry, 51(39), 7651-3 View Abstract

Britz-McKibbin, P, 2012. "New advances in amino acid profiling by capillary electrophoresis-electrospray ionization-mass spectrometry.". Methods Mol Biol, 828, 83-99 View Abstract

2011

Britz-McKibbin, P, 2011. "Capillary electrophoresis-electrospray ionization-mass spectrometry (CE-ESI-MS)-based metabolomics.". Methods Mol Biol, 708, 229-46 View Abstract

Kuehnbaum, N and Britz-McKibbin, P, 2011. "Comprehensive Profiling of Free and Conjugated Estrogens by Capillary Electrophoresis–Time of Flight/Mass Spectrometry". Anal. Chem., 83(21), 8063-8068 View Abstract

Shanmuganathan, M and Britz-McKibbin, P, 2011. "Inhibitor screening of pharmacological chaperones for lysosomal beta-glucocerebrosidase by capillary electrophoresis.". Anal Bioanal Chem, 399(8), 2843-53 View Abstract

2010

D'Agostino, L, Lam, K, Lee, R, and Britz-McKibbin, P, 2010. "Comprehensive Plasma Thiol Redox Status Determination for Metabolomics". J. Proteome Res., 10(2), 592-603 View Abstract

Gavina, JMA, White, CE, Finan, TM, and Britz-McKibbin, P, 2010. "Determination of 4-hydroxyproline-2-epimerase activity by capillary electrophoresis: A stereoselective platform for inhibitor screening of amino acid isomerases.". Electrophoresis, 31(16), 2831-7 View Abstract

Lee, R, West, D, Phillips, SM, and Britz-McKibbin, P, 2010. "Differential metabolomics for quantitative assessment of oxidative stress with strenuous exercise and nutritional intervention: thiol-specific regulation of cellular metabolism with N-acetyl-L-cysteine pretreatment.". Anal Chem, 82(7), 2959-68 View Abstract

Fei, F and Britz-McKibbin, P, 2010. "Direct analysis of polyols using 3-nitrophenylboronic acid in capillary electrophoresis: thermodynamic and electrokinetic principles of molecular recognition.". Anal Bioanal Chem, 398(3), 1349-56 View Abstract

Lee, R and Britz-McKibbin, P, 2010. "Metabolomic studies of radiation-induced apoptosis of human leukocytes by capillary electrophoresis-mass spectrometry and flow cytometry: adaptive cellular responses to ionizing radiation.". Electrophoresis, 31(14), 2328-37 View Abstract

2009

Lee, R and Britz-McKibbin, P, 2009. "Differential rates of glutathione oxidation for assessment of cellular redox status and antioxidant capacity by capillary electrophoresis-mass spectrometry: an elusive biomarker of oxidative stress.". Anal Chem, 81(16), 7047-56 View Abstract

Gavina, JMA, Mazhab-Jafari, MT, Melacini, G, and Britz-McKibbin, P, 2009. "Label-free assay for thermodynamic analysis of protein-ligand interactions: a multivariate strategy for allosteric ligand screening.". Biochemistry, 48(2), 223-5 View Abstract

Chalcraft, KR and Britz-McKibbin, P, 2009. "Newborn screening of inborn errors of metabolism by capillary electrophoresis-electrospray ionization-mass spectrometry: a second-tier method with improved specificity and sensitivity.". Anal Chem, 81(1), 307-14 View Abstract

Chalcraft, KR, Lee, R, Mills, C, and Britz-McKibbin, P, 2009. "Virtual quantification of metabolites by capillary electrophoresis-electrospray ionization-mass spectrometry: predicting ionization efficiency without chemical standards.". Anal Chem, 81(7), 2506-15 View Abstract

2008

Kaiser, C, Segui-Lines, G, D'Amaral, JC, Ptolemy, AS, and Britz-McKibbin, P, 2008. "Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation.". Chem Commun (Camb)(3), 338-40 View Abstract

Ptolemy, AS and Britz-McKibbin, P, 2008. "New advances in on-line sample preconcentration by capillary electrophoresis using dynamic pH junction.". Analyst, 133(12), 1643-8 View Abstract

2007

Segui-Lines, G, Gavina, JMA, D'Amaral, JC, and Britz-McKibbin, P, 2007. "High-throughput screening of holoprotein conformational stability by dynamic ligand exchange-affinity capillary electrophoresis.". Analyst, 132(8), 741-4 View Abstract

Lee, R, Ptolemy, AS, Niewczas, L, and Britz-McKibbin, P, 2007. "Integrative metabolomics for characterizing unknown low-abundance metabolites by capillary electrophoresis-mass spectrometry with computer simulations.". Anal Chem, 79(2), 403-15 View Abstract

Gavina, J and Britz-McKibbin, P, 2007. "Protein Unfolding and Conformational Studies by Capillary Electrophoresis ". Curr. Anal. Chem., 3(1), 17-31 View Abstract

Bernard, E, Britz-McKibbin, P, and Gernigon, N, 2007. "Resveratrol Photoisomerization: An Integrative Guided-Inquiry Experiment". J. Chem. Educ., 84(7), 1159 View Abstract

Ptolemy, AS, Lee, R, and Britz-McKibbin, P, 2007. "Strategies for comprehensive analysis of amino acid biomarkers of oxidative stress.". Amino Acids, 33(1), 3-18 View Abstract

2006

Gavina, JMA, Das, R, and Britz-McKibbin, P, 2006. "Dynamic unfolding of a regulatory subunit of cAMP-dependent protein kinase by capillary electrophoresis: Impact of cAMP dissociation on protein stability.". Electrophoresis, 27(21), 4196-204 View Abstract

Samson, S and Britz-McKibbin, P, 2006. "Enhanced binding and conformational selectivity in affinity capillary electrophoresis using a water-soluble resorcin[4]arene as intrinsic buffer and electrokinetic host.". Electrophoresis, 27(4), 842-51 View Abstract

Ptolemy, AS and Britz-McKibbin, P, 2006. "Sample preconcentration with chemical derivatization in capillary electrophoresis. Capillary as preconcentrator, microreactor and chiral selector for high-throughput metabolite screening.". J Chromatogr A, 1106(1-2), 7-18 View Abstract

Ptolemy, AS, Tran, L, and Britz-McKibbin, P, 2006. "Single-step enantioselective amino acid flux analysis by capillary electrophoresis using on-line sample preconcentration with chemical derivatization.". Anal Biochem, 354(2), 192-204 View Abstract

2005

Ptolemy, AS, Le Bihan, M, and Britz-McKibbin, P, 2005. "On-line sample preconcentration with chemical derivatization of bacterial biomarkers by capillary electrophoresis: a dual strategy for integrating sample pretreatment with chemical analysis.". Electrophoresis, 26(21), 4206-14 View Abstract

Ptolemy, AS and Britz-McKibbin, P, 2005. "Single-step analysis of low abundance phosphoamino acids via on-line sample preconcentration with chemical derivatization by capillary electrophoresis.". Analyst, 130(9), 1263-70 View Abstract

2003

Britz-McKibbin, P, Ichihashi, T, Tsubota, K, Chen, DDY, and Terabe, S, 2003. "Complementary on-line preconcentration strategies for steroids by capillary electrophoresis.". J Chromatogr A, 1013(1-2), 65-76 View Abstract

Markuszewski, MJ, Britz-McKibbin, P, Terabe, S, Matsuda, K, and Nishioka, T, 2003. "Determination of pyridine and adenine nucleotide metabolites in Bacillus subtilis cell extract by sweeping borate complexation capillary electrophoresis.". J Chromatogr A, 989(2), 293-301 View Abstract

Kim, J, Britz-McKibbin, P, Hirokawa, T, and Terabe, S, 2003. "Mechanistic study on analyte focusing by dynamic pH junction in capillary electrophoresis using computer simulation.". Anal Chem, 75(16), 3986-93 View Abstract

Britz-McKibbin, P and Terabe, S, 2003. "On-line preconcentration strategies for trace analysis of metabolites by capillary electrophoresis.". J Chromatogr A, 1000(1-2), 917-34 View Abstract

Britz-McKibbin, P, Markuszewski, MJ, Iyanagi, T, Matsuda, K, Nishioka, T, and Terabe, S, 2003. "Picomolar analysis of flavins in biological samples by dynamic pH junction-sweeping capillary electrophoresis with laser-induced fluorescence detection.". Anal Biochem, 313(1), 89-96 View Abstract

Britz-Mckibbin, P, Nishioka, T, and Terabe, S, 2003. "Sensitive and high-throughput analyses of purine metabolites by dynamic pH junction multiplexed capillary electrophoresis: a new tool for metabolomic studies.". Anal Sci, 19(1), 99-104 View Abstract

2002

Britz-McKibbin, P and Chen, DDY, 2002. "Accurately describing weak analyte-additive interactions by capillary electrophoresis.". Electrophoresis, 23(6), 880-8 View Abstract

Britz-McKibbin, P and Terabe, S, 2002. "High-sensitivity analyses of metabolites in biological samples by capillary electrophoresis using dynamic pH junction-sweeping.". Chem Rec, 2(6), 397-404 View Abstract

Britz-McKibbin, P, Otsuka, K, and Terabe, S, 2002. "On-line focusing of flavin derivatives using Dynamic pH junction-sweeping capillary electrophoresis with laser-induced fluorescence detection.". Anal Chem, 74(15), 3736-43 View Abstract

2000

Britz-McKibbin, P and Chen, DD, 2000. "Selective focusing of catecholamines and weakly acidic compounds by capillary electrophoresis using a dynamic pH junction.". Anal Chem, 72(6), 1242-52 View Abstract

Britz-McKibbin, P, Bebault, GM, and Chen, DD, 2000. "Velocity-difference induced focusing of nucleotides in capillary electrophoresis with a dynamic pH junction.". Anal Chem, 72(8), 1729-35 View Abstract

1999

Britz-Mckibbin, P, Wong, J, and Chen, DD, 1999. "Analysis of epinephrine from fifteen different dental anesthetic formulations by capillary electrophoresis.". J Chromatogr A, 853(1-2), 535-40 View Abstract

Britz-Mckibbin, P, Vo, HC, MacGillivray, RT, and Chen, DD, 1999. "Analysis of gamma-carboxyglutamic acid content of protein, urine, and plasma by capillary electrophoresis and laser-induced fluorescence.". Anal Chem, 71(8), 1633-7 View Abstract

Vo, HC, Britz-Mckibbin, P, Chen, DD, and MacGillivray, RT, 1999. "Undercarboxylation of recombinant prothrombin revealed by analysis of gamma-carboxyglutamic acid using capillary electrophoresis and laser-induced fluorescence.". FEBS Lett, 445(2-3), 256-60 View Abstract

1998

Britz-McKibbin, P and Chen, DD, 1998. "A water-soluble tetraethylsulfonate derivative of 2-methylresorcinarene as an additive for capillary electrophoresis.". Anal Chem, 70(5), 907-12 View Abstract

Britz-Mckibbin, P, Kranack, AR, Paprica, A, and Chen, DD, 1998. "Quantitative assay for epinephrine in dental anesthetic solutions by capillary electrophoresis.". Analyst, 123(7), 1461-3 View Abstract

Kranack, AR, Bowser, MT, Britz-McKibbin, P, and Chen, DD, 1998. "The effects of a mixture of charged and neutral additives on analyte migration behavior in capillary electrophoresis.". Electrophoresis, 19(3), 388-96 View Abstract

1997

Britz-McKibbin, P and Chen, D, 1997. "Prediction of the migration behavior of analytes in capillary electrophoresis based on three fundamental parameters". J. Chromatogr. A, 781(1-2), 23-34 View Abstract

Peng, X, Bowser, MT, Britz-McKibbin, P, Bebault, GM, Morris, JR, and Chen, DD, 1997. "Quantitative description of analyte migration behavior based on dynamic complexation in capillary electrophoresis with one or more additives.". Electrophoresis, 18(5), 706-16 View Abstract

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